Alfred Amambua-Ngwa is an MRC Investigator at the MRC Unit The Gambia at London school of Hygiene and Tropical Medicine. He obtained a PhD in Biochemistry and Molecular Biology from the University of Buea in Cameroon in November 2004. He moved to the MRC Unit in The Gambia for Postdoctoral research in 2006. He currently leads a local team and several research consortia across Africa with a research focus on the population genomics and epidemiology of malaria. He participates in several capacity development initiatives in Africa, including, H3Africa, WANETAM and DELTAS (WACCBIP and DELGEME).

Alfred’s research at graduate and early Postdoctoral studies (Universities of Salford and Nottingham, UK and Lund, Sweden) employed biochemical and molecular biology assays to detect and characterised antigens involved in host-pathogen interactions in onchocerciasis. His current research employs population genomics to determine genome-wide signatures of selection, patterns of transmission and adaptation of Plasmodium falciparum malaria parasite to drugs and environment.

He leads several funded projects, generating thousands of genomes and polymorphism of P. falciparum and the anopheline vector. This data and those from the H3Africa project offers great potential for answering fundamental malaria evolutionary biology questions as well as enable the development of new tools against the disease


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